naive estimate of coverage of all SNPs in the genome (G)
\[ \frac{T+L}{R} \]
R: a reference set of SNPs T: tag SNPs L: SNPs are in LD with a SNP in T
corrected genomewide coverage
\[ \frac{\frac{L}{R-T}(G-T)+T}{G} \]
G: the number of common SNPs in the genome.
Reference
- Jeffrey C Barrett & Lon R Cardon. Evaluating coverage of genome-wide association studies. NATURE GENETICS, VOLUME 38, NUMBER 6, PAGE 656-662, JUNE 2006.